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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Noninvasive LV pressure estimation using subharmonic emissions from microbubbles
JACC. Cardiovascular imaging, v 5(1), pp 87-92
Jan 2012
PMID: 22239898
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To develop a new noninvasive approach to quantify left ventricular (LV) pressures using subharmonic emissions from microbubbles, an ultrasound scanner was used in pulse inversion grayscale mode; unprocessed radiofrequency data were obtained with pulsed wave Doppler from the aorta and/or LV during Sonazoid infusion. Subharmonic data (in dB) were extracted and processed. Calibration factor (mm Hg/dB) from the aortic pressure was used to estimate LV pressures. Errors ranged from 0.19 to 2.50 mm Hg when estimating pressures using the aortic calibration factor, and were higher (0.64 to 8.98 mm Hg) using a mean aortic calibration factor. Subharmonic emissions from ultrasound contrast agents have the potential to noninvasively monitor LV pressures.
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Details
- Title
- Noninvasive LV pressure estimation using subharmonic emissions from microbubbles
- Creators
- Jaydev K Dave - Thomas Jefferson UniversityValgerdur G Halldorsdottir - Thomas Jefferson UniversityJohn R Eisenbrey - Thomas Jefferson UniversityJoel S Raichlen - Thomas Jefferson UniversityJi-Bin Liu - Thomas Jefferson UniversityMaureen E McDonald - Thomas Jefferson UniversityKris Dickie - Ultrasonix Medical Corporation, Richmond, British Columbia, CanadaShumin Wang - Thomas Jefferson UniversityCorina Leung - Ultrasonix Medical Corporation, Richmond, British Columbia, CanadaFlemming Forsberg - Thomas Jefferson University
- Publication Details
- JACC. Cardiovascular imaging, v 5(1), pp 87-92
- Publisher
- Elsevier
- Grant note
- R21 HL081892 / NHLBI NIH HHS RC1 DK087365 / NIDDK NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000299392300013
- Scopus ID
- 2-s2.0-84862909261
- Other Identifier
- 991019350684204721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Radiology, Nuclear Medicine & Medical Imaging