Journal article
Normal development of tyrosine hydroxylase and serotonin immunoreactive fibers innervating anterior cingulate cortex and visual cortex in rabbits exposed prenatally to cocaine
Brain research, v 715(1), pp 221-224
1996
PMID: 8739642
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Anterior cingulate cortex develops abnormally in rabbits exposed to cocaine in utero but visual cortex is normal. The interactions of cocaine with the dopamine, norepinephrine and serotonin systems makes each a potential candidate for influencing these developmental effects. Here, we report no differences in the distribution and density of serotonin and tyrosine hydroxylase-immunoreactive fibers in the anterior cingulate cortex in postnatal rabbits exposed prenatally to cocaine or saline. Because the pattern and extent of cortical innervation by these systems appears normal, the data suggest that the effects of prenatal exposure to cocaine may involve changes in monoamine signaling distinct from morphological reorganization of the cortical afferents.
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Details
- Title
- Normal development of tyrosine hydroxylase and serotonin immunoreactive fibers innervating anterior cingulate cortex and visual cortex in rabbits exposed prenatally to cocaine
- Creators
- Xiao-Hui Wang - Department of Anatomy and Neurobiology, Medical College of Pensylvania, Philadelphia, PA 19129, USAPat Levitt - Department of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, UMDNJ, Piscataway, NJ 08854, USAAnn O'Brien Jenkins - Department of Anatomy and Neurobiology, Medical College of Pensylvania, Philadelphia, PA 19129, USAE Hazel Murphy - Department of Anatomy and Neurobiology, Medical College of Pensylvania, Philadelphia, PA 19129, USA
- Publication Details
- Brain research, v 715(1), pp 221-224
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1996UK60900027
- Scopus ID
- 2-s2.0-0029988022
- Other Identifier
- 991014878137904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Neurosciences