Journal article
Novel Defense Peptides from Platelets Kill Malaria Parasites
Trends in parasitology, v 34(9), pp 729-731
01 Sep 2018
PMID: 30098918
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
PF4 (platelet factor 4) is the first host defense peptide identified from platelets that kills malaria parasites. In a recent study, a cyclic PF4 derivative, cPF4PD, is developed, which inherits the antiparasitic effect of PF4 but excludes its potential side effects. cPF4PD is a promising novel antimalarial agent of human origin.
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Details
- Title
- Novel Defense Peptides from Platelets Kill Malaria Parasites
- Creators
- Michael W. Mather - Drexel UniversityHangjun Ke - Drexel University
- Publication Details
- Trends in parasitology, v 34(9), pp 729-731
- Publisher
- Elsevier
- Number of pages
- 4
- Grant note
- R01 AI028398; K22 AI127702 / NIAID NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000444526700002
- Scopus ID
- 2-s2.0-85051073332
- Other Identifier
- 991019168999704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Parasitology