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Novel cutaneous uses for botulinum toxin type A
Journal article   Peer reviewed

Novel cutaneous uses for botulinum toxin type A

Cheryl Bansal, Kenny J Omlin, Christine M Hayes and Thomas E Rohrer
Journal of cosmetic dermatology, v 5(3), pp 268-272
Sep 2006
DOI: https://doi.org/10.1111/j.1473-2165.2006.00255.x
PMID: 17177750

Abstract

Administration, Cutaneous Botulinum Toxins, Type A - administration & dosage Botulinum Toxins, Type A - therapeutic use Humans Neuromuscular Agents - administration & dosage Neuromuscular Agents - therapeutic use Skin Diseases - drug therapy Wound Healing
Botulinum toxin type A is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It has been used extensively in the field of dermatology for the treatment of dynamic rhytides and in the treatment of hyperhidrosis. Botulinum toxin has an excellent safety profile and few side effects when used for these purposes. Recently, botulinum toxin has also been used experimentally in a number of other dermatologic conditions with good results. These conditions include: persistent facial flushing, gustatory sweating and epiphora, anal fissures, familial benign pemphigus (Hailey-Hailey disease), dyshidrotic eczema, and following surgical wound closures. While randomized, controlled prospective trials are still needed to further understand the efficacy and safety of botulinum toxin in these conditions, anecdotal and case report data suggest that botulinum toxin is both safe and efficacious in these and many other procedures.

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