Journal article
Nucleus implant parameters significantly change the compressive stiffness of the human lumbar intervertebral disc
Journal of biomechanical engineering, v 127(3), pp 536-540
Jun 2005
PMID: 16060361
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Nucleus replacement by a synthetic material is a recent trend for treatment of lower back pain. Hydrogel nucleus implants were prepared with variations in implant modulus, height, and diameter Human lumbar intervertebral discs (IVDs) were tested in compression for intact, denucleated, and implanted condition. Implantation of nucleus implants with different material and geometric parameters into a denucleated IVD significantly altered the IVD compressive stiffness. Variations in the nucleus implant parameters significantly change the compressive stiffness of the human lumbar IVD. Implant geometrical variations were more effective than those of implant modulus variations in the range examined.
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Details
- Title
- Nucleus implant parameters significantly change the compressive stiffness of the human lumbar intervertebral disc
- Creators
- Abhijeet Joshi - Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USASamir MehtaEdward VresilovicAndrew KardunaMichele Marcolongo
- Publication Details
- Journal of biomechanical engineering, v 127(3), pp 536-540
- Publisher
- ASME; United States
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000230050100020
- Scopus ID
- 2-s2.0-21144441981
- Other Identifier
- 991014877951104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biophysics
- Engineering, Biomedical