Occupational characteristics and the progression of carotid artery intima-media thickness and plaque over 9 years: the Multi-Ethnic Study of Atherosclerosis (MESA)
Kaori Fujishiro, Ana V. Diez Roux, Paul Landsbergis, Joel D. Kaufman, Claudia E. Korcarz and James H. Stein
Occupational and environmental medicine (London, England), v 72(10), pp 690-698
Life Sciences & Biomedicine Public, Environmental & Occupational Health Science & Technology
Objectives The role of occupation in the development of cardiovascular disease (CVD) remains a topic of research because few studies have examined longitudinal associations, and because occupation can be an indicator of socioeconomic position (SEP) and a proxy for hazard exposure. This study examines associations of occupational category as an SEP marker and selected occupational exposures with progression of the subclinical carotid artery disease.
Methods A community-based, multiethnic sample (n=3109, mean age=60.2) provided subclinical CVD measures at least twice at three data collection points (mean follow-up=9.4 years). After accounting for demographic characteristics, SEP, and traditional CVD risk factors, we modelled common carotid intima-media thickness, carotid plaque scores, and carotid plaque shadowing as a function of occupational category, physical hazard exposure, physical activity on the job, interpersonal stress, job control and job demands. These job characteristics were derived from the Occupational Resource Network (O*NET). Random coefficient models were used to account for repeated measures and time-varying covariates.
Results There were a few statistically significant associations at baseline. After all covariates were included in the model, men in management, office/sales, service and blue-collar jobs had 28-44% higher plaque scores than professionals at baseline (p=0.001). Physically hazardous jobs were positively associated with plaque scores among women (p=0.014). However, there were no significant longitudinal associations between any of the occupational characteristics and any of the subclinical CVD measures.
Conclusions There was little evidence that the occupational characteristics examined in this study accelerated the progression of subclinical CVD.
Occupational characteristics and the progression of carotid artery intima-media thickness and plaque over 9 years: the Multi-Ethnic Study of Atherosclerosis (MESA)
Creators
Kaori Fujishiro - National Institute for Occupational Safety and Health
Ana V. Diez Roux - Drexel University
Paul Landsbergis - State University of New York
Joel D. Kaufman - University of Washington
Claudia E. Korcarz - University of Wisconsin
James H. Stein - University of Wisconsin
Publication Details
Occupational and environmental medicine (London, England), v 72(10), pp 690-698
Publisher
Bmj Publishing Group
Number of pages
9
Grant note
N01-HC-95159; N01-HC-95160; N01-HC-95161; N01-HC-95162; N01-HC-95163; N01-HC-95164; N01-HC-95165; N01-HC-95166; N01-HC-95167; N01-HC-95168; N01-HC-95169; R01-HL-101161 / National Heart, Lung and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI)
N01HC095163 / DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
UL1-RR-024156; UL1-RR-025005 / NCRR; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR)
FY08 CRN SLB8 / National Institute for Occupational Safety and Health Intramural funds (NORA)
UL1RR024156 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR)
R01HL101161 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI)
RD831697 / US Environmental Protection Agency; United States Environmental Protection Agency
Resource Type
Journal article
Language
English
Academic Unit
Urban Health Collaborative
Web of Science ID
WOS:000361498700003
Scopus ID
2-s2.0-84941757275
Other Identifier
991019169800704721
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