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Journal article
On the assessment of oxidative and microstructural changes after in vivo degradation of historical UHMWPE knee components by means of vibrational spectroscopies and nanoindentation
Journal of biomedical materials research. Part A, v 89A(2), pp 530-538
01 May 2009
PMID: 18435407
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This study reports on the suitability of different experimental techniques to evaluate chemical, microstructural, and mechanical changes associated with in vivo oxidation encountered in historical polyethylene components. To accomplish this aim, eight traceable tibial inserts were analyzed after revision Surgery. The knee bearings were gamma sterilized in air and implanted for an average of 11.5 years after a shelf life of no longer than 1 year. Characterization of oxidation and transvinylene indexes, crystallinity, amorphous, and intermediate phase fractions, along with hardness and surface modulus, were performed in transverse sections of each bearing using Fourier transform infrared spectroscopy, Raman spectroscopy, and nanoindentation respectively. Generally, subsurface maxima in the crystallinity, oxidation index, and hardness were observed at a depth of about 1 mm in all of the bearings. The superior Surfaces and anterior-posterior faces of the inserts exhibited significantly higher oxidation and greater crystallinity than the inferior side. These observations suggest that the metallic tray may limit the access of molecular oxygen to the backside of the tibial inserts. We conclude that chemical, physical, and mechanical properties data confirm the occurrence of in vivo degradation in the long-term implanted knee components following gamma irradiation in air. Furthermore, infrared spectroscopy alone appeared to provide excellent insight into the oxidation and crystallization state of the in vivo oxidized polyethylene. (C) 2008 Wiley Periodicals, Inc. J Biomed Mater Res 89A: 530-538, 2009
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Details
- Title
- On the assessment of oxidative and microstructural changes after in vivo degradation of historical UHMWPE knee components by means of vibrational spectroscopies and nanoindentation
- Creators
- Francisco J. Medel - Drexel UniversityClare M. Rimnac - Case Western Reserve UniversitySteven M. Kurtz - Exponent (United States)
- Publication Details
- Journal of biomedical materials research. Part A, v 89A(2), pp 530-538
- Publisher
- Wiley
- Number of pages
- 9
- Grant note
- R01AR047904 / NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS) R01 AR47904 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Sulzer Zimmer, Inc.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000264850200026
- Scopus ID
- 2-s2.0-65549122480
- Other Identifier
- 991019167805004721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Materials Science, Biomaterials