Journal article
One-year Weight Losses in the Look AHEAD Study: Factors Associated With Success
Obesity (Silver Spring, Md.), v 17(4), pp 713-722
01 Apr 2009
PMID: 19180071
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This report provides a further analysis of the first year weight losses in the Look AHEAD (Action for Health in Diabetes) study and identifies factors associated with success. Participants were a total of 5,145 men and women with type 2 diabetes who were recruited at 16 sites and randomly assigned to an intensive lifestyle intervention (ILI) or a control condition, Diabetes Support and Education (DSE). During year 1, participants in ILI received comprehensive diet and physical activity counseling in a total of 42 group and individual sessions, compared with three educational sessions for DSE participants. As reported previously, at the end of the year, ILI participants lost 8.6% of initial weight, compared to 0.7% for DSE (P < 0.001). Within the ILI group, all racial/ethnic groups achieved clinically significant weight losses (>5.5%), although there were significant differences among groups. For the year, ILI participants attended an average of 35.4 treatment sessions and reported exercising a mean of 136.6 min/week and consuming a total of 360.9 meal replacement products. Greater self-reported physical activity was the strongest correlate of weight loss, followed by treatment attendance and consumption of meal replacements. The use of orlistat, during the second half of the year, increased weight loss only marginally in those ILI participants who had lost <5% of initial weight during the first 6 months and chose to take the medication thereafter as a toolbox option. The lifestyle intervention was clinically effective in all subsets of an ethnically and demographically diverse population.
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Details
- Title
- One-year Weight Losses in the Look AHEAD Study: Factors Associated With Success
- Creators
- Thomas A. Wadden - University of PennsylvaniaDelia S. West - University of Arkansas for Medical SciencesRebecca H. Neiberg - Wake Forest UniversityRena R. Wing - Miriam HospitalDonna H. Ryan - Pennington Biomedical Research CenterKaren C. Johnson - University of Tennessee Health Science CenterJohn P. Foreyt - Baylor College of MedicineJames O. Hill - University of Colorado Anschutz Medical CampusDace L. Trence - University of WashingtonMara Z. Vitolins - Wake Forest UniversityLook AHEAD Res GrpEllen Stephanie Krauthamer Ewing - Drexel University
- Publication Details
- Obesity (Silver Spring, Md.), v 17(4), pp 713-722
- Publisher
- Wiley
- Number of pages
- 10
- Grant note
- Centers for Disease Control and Prevention; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA National Center on Minority Health and Health Disparities; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Minority Health & Health Disparities (NIMHD) National Heart, Lung, and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) M01RR002719 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) M01RR00005644 / University of Pittsburgh M01RR01066 / Massachusetts General Hospital Mallinckrodt General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) M01RR01346 / University of Washington/VA Puget Sound Health Care System Medical Research Service, Department of Veterans Affairs; University of Washington; US Department of Veterans Affairs M01RR02719 / Johns Hopkins Medical Institutions National Institute of Nursing Research; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Nursing Research (NINR) M01RR00051 / University of Colorado Health Sciences Center General Clinical Research Center; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) M01RR0021140 / University of Tennessee P30 DK48520 / Clinical Nutrition Research Unit National Institute of Diabetes and Digestive and Kidney Diseases; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) DK57136; DK57149; DK56990; DK57177; DK57171; DK57151; DK57182; DK57131; DK57002; DK57078; DK57154; DK57178; DK57219; DK57008; DK57135; DK56992; DK 046204 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA U01DK057171 / NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) Office of Research on Women's Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Office of Research on Women's Health (ORWH)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Counseling and Family Therapy; Drexel University
- Web of Science ID
- WOS:000264658800023
- Scopus ID
- 2-s2.0-63049083098
- Other Identifier
- 991020100084904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Endocrinology & Metabolism
- Nutrition & Dietetics