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Ordered, adherent layers of nanofibers enabled by supramolecular interactions
Journal article   Open access

Ordered, adherent layers of nanofibers enabled by supramolecular interactions

Christopher B. Highley, Christopher B. Rodell, Iris L. Kim, Ryan J. Wade and Jason A. Burdick
Journal of materials chemistry. B, Materials for biology and medicine, v 2(46), pp 8110-8115
01 Jan 2014
PMID: 25408916
url
https://europepmc.org/articles/pmc4232958View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Materials Science Materials Science, Biomaterials Science & Technology Technology
Aligned nanofibrous substrates can be created by electrospinning, but methods for creating multilamellar structures of aligned fibers are limited. Here, apposed nanofibrous scaffolds with pendant beta-cyclodextrin (CD) were adhered together by adamantane (Ad) modified hyaluronic acid, exploiting the guest-host interactions of CD and Ad for macroscopic assembly. Stable user-defined multi-layered scaffolds were formed for cell culture or tissue engineering.

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Web of Science research areas
Materials Science, Biomaterials
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