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Outcomes of Ahmed glaucoma valve and transscleral cyclophotocoagulation in neovascular glaucoma
Journal article   Open access   Peer reviewed

Outcomes of Ahmed glaucoma valve and transscleral cyclophotocoagulation in neovascular glaucoma

Wesam S Shalaby, Allen Y Ganjei, Brian Wogu, Jonathan S Myers, Marlene R Moster, Reza Razeghinejad, Daniel Lee, Natasha N Kolomeyer, Tarek E Eid, L Jay Katz, …
Indian journal of ophthalmology, v 70(4), pp 1253-1259
Apr 2022
DOI: https://doi.org/10.4103/ijo.IJO_2107_21
PMID: 35326027
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.4103/ijo.ijo_2107_21View
Published, Version of Record (VoR) Open
url
https://doi.org/10.4103/ijo.IJO_2107_21View
Published, Version of Record (VoR) Open

Abstract

Follow-Up Studies Glaucoma - surgery Glaucoma Drainage Implants Glaucoma, Neovascular - diagnosis Glaucoma, Neovascular - surgery Humans Intraocular Pressure Laser Coagulation Retrospective Studies Treatment Outcome
To determine the outcomes of Ahmed glaucoma valve (AGV) and transscleral diode cyclophotocoagulation (CPC) in neovascular glaucoma (NVG). This was a single-center retrospective comparative case series involving chart review of consecutive patients who underwent AGV or CPC for treatment of NVG and had ≥6 months of follow-up. Surgical failure at 6 months, defined as an IOP of >21 or <6 mm Hg with hypotony maculopathy after 1 month, progression to no light perception (NLP) vision, glaucoma reoperation, or removal of AGV were the main outcome measures. In total, 121 eyes of 121 patients were included (70 AGV and 51 CPC). Baseline demographics, visual acuity (VA), and intraocular pressure (IOP) were comparable between groups. At 6 months, failure was significantly higher in the CPC group than in the AGV group (43.1% vs. 17.1%, P = 0.020). Both groups had similar IOP and medication number at 6 months, but VA was significantly lower in the CPC group compared to the AGV group (2.4 ± 0.8 vs. 1.9 ± 1.0, P = 0.017). More CPC eyes required reoperation for glaucoma than AGV eyes (11.8% vs. 1.4%, P = 0.041). Multivariate regression analysis identified higher preoperative IOP (P = 0.001) and CPC surgery (P = 0.004) as independent predictors of surgical failure at 6 months. Age, sex, race, NVG etiology, bilaterality of the underlying retinal pathology, perioperative retina treatment, and prior or combined vitrectomy were not significant. AGV and CPC had comparable IOP and medication reduction in NVG eyes at 6 months. CPC was more frequently associated with failure, reoperation for glaucoma, and worse visual outcomes. High preoperative IOP and CPC surgery independently predicted surgical failure.

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8 citations in Web of Science
7 citations in Scopus

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Domestic collaboration
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Web of Science research areas
Ophthalmology
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