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Oxidation of enamines to α-hydroxy ketones and α-amino ketones using N-sulfonyloxaziridines
Journal article   Peer reviewed

Oxidation of enamines to α-hydroxy ketones and α-amino ketones using N-sulfonyloxaziridines

Franklin A. Davis and Aurelia C. Sheppard
Tetrahedron letters, v 29(35), pp 4365-4368
1988

Abstract

Tri-substituted enamines are oxidized to α-hydroxy ketones by N-sulfonyloxaziridines while di-substituted enamines are oxidized to α-amino ketones. A unified mechanism for the formation of both α-hydroxy ketones and α-amino ketones is proposed. Tri-substituted enamines are oxidized to α-hydroxy ketones by N-sulfonyloxaziridines [ O] while di-substituted enamines are oxidized to α-amino ketones. A unified mechanism for the formation of both α-hydroxy ketones and α-amino ketones is proposed.

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Web of Science research areas
Chemistry, Organic
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