Journal article
Pain of Injection and Duration of Anesthesia for Intradermal Infiltration of Lidocaine, Bupivacaine, and Etidocaine
The Journal of Dermatologic Surgery and Oncology, v 20(7), pp 459-464
Jul 1994
PMID: 8034840
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
background. Bupivacaine and etidocaine are local anesthetics said to be long acting based on nerve block data. There are insufficient data on pain of infiltration and duration of anesthesia when either is used for dermal infiltration to assess suitability for skin surgery.
objective. We conducted a randomized, placebo‐controlled, double‐blinded comparison of intradermal 1 % etidocaine, 0.5% bupivacaine, and 2% lidocaine for pain of injection and duration of anesthesia.
methods. Twenty subjects received the above three agents plus normal saline, each with and without epinephrine 1:200,000, with all solutions adjusted to pH 5.95 ± 0.15.
results. Lidocaine hurt least and etidocaine hurt most. Adrenalized solutions were more painful than plain. For plain solutions bupivacaine lasted longest and lidocaine lasted shortest by far. For adrenalized solutions bupivacaine lasted 27% longer than lidocaine and 45% longer than etidocaine.
conclusion. Where epinephrine is contraindicated and long anesthesia matters, use plain bupivacaine. When epinephrine can be used, lidocaine lasts almost as long as bupivacaine and hurts less.
Metrics
Details
- Title
- Pain of Injection and Duration of Anesthesia for Intradermal Infiltration of Lidocaine, Bupivacaine, and Etidocaine
- Creators
- NATHAN R. Howe - Hahnemann University HospitalJOHN M. Williams - Hahnemann University HospitalJoseph M Williams - [Retired Faculty]
- Publication Details
- The Journal of Dermatologic Surgery and Oncology, v 20(7), pp 459-464
- Publisher
- Blackwell Publishing Ltd
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1994NZ39700006
- Scopus ID
- 2-s2.0-0027987956
- Other Identifier
- 991019183959604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Dermatology
- Oncology
- Surgery