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Palladium(0)-catalyzed conversion of vinyl trifluoromethanesulfonates into α,β-unsaturated nitriles
Journal article   Peer reviewed

Palladium(0)-catalyzed conversion of vinyl trifluoromethanesulfonates into α,β-unsaturated nitriles

Edward Piers and Fraser F. Fleming
Canadian journal of chemistry, v 71(11), pp 1867-1872
01 Nov 1993

Abstract

Treatment (benzene, room temperature) of each of the vinyl trifluoromethanesulfonates 16–23 with dry lithium cyanide in the presence of catalytic amounts of tetrakis(triphenylphosphine)palladium(0) and the crown ether 12-crown-4 provides good to excellent yields of the corresponding α,β-unsaturated nitriles 24–31.

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Chemistry, Multidisciplinary
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