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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Particles and microfluidics merged: perspectives of highly sensitive diagnostic detection
Mikrochimica acta (1966), v 176(3-4), pp 251-269
01 Feb 2012
PMID: 25378716
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
There is a growing need for diagnostic technologies that provide laboratories with solutions that improve quality, enhance laboratory system productivity, and provide accurate detection of a broad range of infectious diseases and cancers. Recent advances in micro- and nanoscience and engineering, in particular in the areas of particles and microfluidic technologies, have advanced the "lab-on-a-chip" concept towards the development of a new generation of point-of-care diagnostic devices that could significantly enhance test sensitivity and speed. In this review, we will discuss many of the recent advances in microfluidics and particle technologies with an eye towards merging these two technologies for application in medical diagnostics. Although the potential diagnostic applications are virtually unlimited, the most important applications are foreseen in the areas of biomarker research, cancer diagnosis, and detection of infectious microorganisms.
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Details
- Title
- Particles and microfluidics merged: perspectives of highly sensitive diagnostic detection
- Creators
- Tania Konry - Shriners Hospitals for Children - ErieShyam Sundhar Bale - Shriners Hospitals for Children - ErieAbhinav Bhushan - Shriners Hospitals for Children - ErieKeyue Shen - Shriners Hospitals for Children - ErieErkin Seker - University of California, DavisBoris Polyak - Drexel UniversityMartin Yarmush - Shriners Hospitals for Children - Erie
- Publication Details
- Mikrochimica acta (1966), v 176(3-4), pp 251-269
- Publisher
- Springer Nature
- Number of pages
- 19
- Grant note
- P41 EB002503 / NIBIB NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Biomedical Imaging & Bioengineering (NIBIB) P41EB002503 / NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Biomedical Imaging & Bioengineering (NIBIB)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000299921400001
- Scopus ID
- 2-s2.0-84856305078
- Other Identifier
- 991019169803604721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Chemistry, Analytical