Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Past year non-medical opioid use and abuse and PTSD diagnosis: Interactions with sex and associations with symptom clusters
Addictive behaviors, v 58, pp 167-174
01 Jul 2016
PMID: 26946448
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Few studies have examined the associations between posttraumatic stress disorder (PTSD) and non-medical opioid use (NMOU), particularly in general U.S. samples.
We analyzed data from wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally representative sample of non-institutionalized adults, to examine (1) the relationship between PTSD diagnosis with NMOU, Opioid Use Disorder diagnosis, and average monthly frequency of NMOU; and (2) the relationship between PTSD symptom clusters with NMOU, Opioid Use Disorder diagnosis, and average monthly frequency of NMOU. We also explored sex differences among these associations.
In the adjusted model, a past year PTSD diagnosis was associated with higher odds of past year NMOU for women and men, but the association was stronger for women. In addition, PTSD was associated with higher odds of an Opioid Use Disorder diagnosis for women, but not for men. With regard to the relationship between specific symptom clusters among those with a past year PTSD diagnosis, important sex differences emerged. For women, the avoidance symptom cluster was associated with higher odds of NMOU, an Opioid Use Disorder diagnosis, and higher rate of average monthly frequency of NMOU, while for men the arousal/reactivity cluster was associated with higher odds of NMOU, an Opioid Use Disorder diagnosis, and a higher rate of average monthly frequency of NMOU. In addition, for men, the avoidance symptom cluster was associated with higher odds of an Opioid Use Disorder diagnosis, but a lower rate of average monthly frequency of NMOU.
Results add to the literature showing an association between PTSD and NMOU and suggest that PTSD is more strongly associated with substance use for women than men. Further, results based on individual symptom clusters suggest that men and women with PTSD may be motivated to use substances for different reasons.
•PTSD was associated with higher odds of non-medical opioid use (NMOU).•These associations between PTSD and NMOU and abuse were stronger for women than men.•There were sex differences in the associations for PTSD symptom clusters and NMOU.
Metrics
Details
- Title
- Past year non-medical opioid use and abuse and PTSD diagnosis: Interactions with sex and associations with symptom clusters
- Creators
- Kathryn Z. Smith - Wayne State UniversityPhilip H. Smith - Yale UniversitySarah A. Cercone - University at Buffalo, State University of New YorkSherry A. McKee - Yale UniversityGregory G. Homish - University at Buffalo, State University of New York
- Publication Details
- Addictive behaviors, v 58, pp 167-174
- Publisher
- Elsevier
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- A.J. Drexel Autism Institute
- Web of Science ID
- WOS:000374360800029
- Scopus ID
- 2-s2.0-84959352101
- Other Identifier
- 991022031022604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology, Clinical
- Substance Abuse