Journal article
Patient‐Specific Self‐Powered Metamaterial Implants for Detecting Bone Healing Progress
Advanced functional materials, v 32(32), 2203533
01 Aug 2022
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
There is an unmet need for developing a new class of smart medical implants with novel properties and advanced functionalities. Here, the concept of “self‐aware implants” is proposed to enable the creation of a new generation of multifunctional metamaterial implantable devices capable of responding to their environment, empowering themselves, and self‐monitoring their condition. These functionalities are achieved via integrating nano energy harvesting and mechanical metamaterial design paradigms. Various aspects of the proposed concept are highlighted by developing proof‐of‐concept interbody spinal fusion cage implants with self‐sensing, self‐powering, and mechanical tunability features. Bench‐top testing is performed using synthetic biomimetic and human cadaver spine models to evaluate the electrical and mechanical performance of the developed patient‐specific metamaterial implants. The results show that the self‐aware cage implants can diagnose bone healing process using the voltage signals generated internally through their built‐in contact‐electrification mechanisms. The voltage and current generated by the implants under the axial compression forces of the spine models reach 9.2 V and 4.9 nA, respectively. The metamaterial implants can serve as triboelectric nanogenerators to empower low‐power electronics. The capacity of the proposed technology to revolutionize the landscape of implantable devices and to achieve better surgical outcomes is further discussed.
A new generation of patient‐specific metamaterial orthopedic implants with diagnostic capabilities is presented. The proposed metamaterial implants can respond to their environment, empower themselves, and self‐monitor their condition. Bench‐top tests are performed using synthetic biomimetic and human cadaver spine models.
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Details
- Title
- Patient‐Specific Self‐Powered Metamaterial Implants for Detecting Bone Healing Progress
- Creators
- Kaveh Barri - University of PittsburghQianyun Zhang - University of PittsburghIsaac Swink - Allegheny Health NetworkYashar Aucie - University of PittsburghKyle Holmberg - Allegheny Health NetworkRyan Sauber - Allegheny Health NetworkDaniel T. Altman - Allegheny Health NetworkBoyle C. Cheng - Allegheny Health NetworkZhong Lin Wang - Georgia Institute of TechnologyAmir H. Alavi - University of Pittsburgh
- Publication Details
- Advanced functional materials, v 32(32), 2203533
- Publisher
- Wiley
- Number of pages
- 11
- Grant note
- Swanson School of Engineering at the University of Pittsburgh (US2022/0011176A1) National Institutes of Health (R21AR075242‐01)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Orthopedic/Orthopaedic Surgery; Surgery
- Web of Science ID
- WOS:000796768700001
- Scopus ID
- 2-s2.0-85132594207
- Other Identifier
- 991021897408604721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Chemistry, Multidisciplinary
- Chemistry, Physical
- Materials Science, Multidisciplinary
- Nanoscience & Nanotechnology
- Physics, Applied
- Physics, Condensed Matter