Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey

Mara A McAdams-DeMarco; Sarah E Van Pilsum Rasmussen; Nadia M Chu; Dayawa Agoons; Ronald F Parsons; Tarek Alhamad; Kirsten L Johansen; Stefan G Tullius; Raymond Lynch; Meera N Harhay; Maya K Rao; Joseph Berger; Matthew Cooper; Jane C Tan; XingXing S Cheng; Kenneth J Woodside; Sandesh Parajuli; Krista L Lentine; Bruce Kaplan; Dorry L Segev; Jon A Kobashigawa; Darshana Dadhania; AST Kidney Pancreas Community of Practice Workgroup

doi:10.1097/TP.0000000000002779

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Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey

Journal article

Open access

Peer reviewed

Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey

Mara A McAdams-DeMarco, Sarah E Van Pilsum Rasmussen, Nadia M Chu, Dayawa Agoons, Ronald F Parsons, Tarek Alhamad, Kirsten L Johansen, Stefan G Tullius, Raymond Lynch, Meera N Harhay, …

Transplantation, v 104(2), pp 349-356

Feb 2020

DOI: https://doi.org/10.1097/TP.0000000000002779

PMID: 31343576

Featured in Collection : UN Sustainable Development Goals @ Drexel

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https://journals.lww.com/transplantjournal/Fulltext/2020/02000/Perceptions_and_Practices_Regarding_Frailty_in.24.aspxView

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Abstract

Aged

Female

Frailty - complications

Frailty - epidemiology

Humans

Incidence

Kidney Failure, Chronic - complications

Kidney Failure, Chronic - epidemiology

Kidney Failure, Chronic - surgery

Kidney Transplantation - methods

Male

Middle Aged

Postoperative Complications - epidemiology

Prospective Studies

Registries

Risk Factors

Societies, Medical

Transplant Recipients

United States - epidemiology

Given the potential utility of frailty, a clinical phenotype of decreased physiologic reserve and resistance to stressors, to predict postkidney transplant (KT) outcomes, we sought to understand the perceptions and practices regarding frailty measurement in US KT programs. Surveys were emailed to American Society of Transplantation Kidney/Pancreas Community of Practice members and 202 US transplant programs (November 2017 to April 2018). Program characteristics were gleaned from Scientific Registry of Transplant Recipients. The 133 responding programs (response rate = 66%) represented 77% of adult KTs and 79% of adult KT candidates in the United States. Respondents considered frailty to be a useful concept in evaluating candidacy (99%) and endorsed a need to develop a frailty measurement specific to KT (92%). Frailty measurement was more common during candidacy evaluation (69%) than during KT admission (28%). Of the 202 programs, 38% performed frailty assessments in all candidates while 23% performed assessments only for older candidates. There was heterogeneity in the frailty assessment method; 18 different tools were utilized to measure frailty. The most common tool was a timed walk test (19%); 67% reported performing >1 tool. Among programs that measure frailty, 53% reported being less likely to list frail patients for KT. Among US KT programs, frailty is recognized as a clinically relevant construct and is commonly measured at evaluation. However, there is considerable heterogeneity in the tools used to measure frailty. Efforts to identify optimal measurement of frailty using either an existing or a novel tool and subsequent standardization of its measurement and application across KT programs should be considered.

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83 citations in Web of Science

78 citations in Scopus

Details

Title: Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey
Creators: Mara A McAdams-DeMarco - Bloomberg (United States)
Sarah E Van Pilsum Rasmussen - Johns Hopkins Medicine
Nadia M Chu - Bloomberg (United States)
Dayawa Agoons - Johns Hopkins Medicine
Ronald F Parsons - Emory University
Tarek Alhamad - Washington University in St. Louis
Kirsten L Johansen - Hennepin County Medical Center
Stefan G Tullius - Brigham and Women's Hospital
Raymond Lynch - Emory University
Meera N Harhay - Drexel University
Maya K Rao - Columbia University
Joseph Berger - The University of Texas Southwestern Medical Center
Matthew Cooper - Georgetown University
Jane C Tan - Stanford University
XingXing S Cheng - Stanford University
Kenneth J Woodside - University of Michigan
Sandesh Parajuli - University of Wisconsin School of Medicine and Public Health
Krista L Lentine - Center for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO
Bruce Kaplan - Baylor Scott & White Health
Dorry L Segev - Saint Louis University
Jon A Kobashigawa - Cedars-Sinai Medical Center
Darshana Dadhania - Cornell University
AST Kidney Pancreas Community of Practice Workgroup
Publication Details: Transplantation, v 104(2), pp 349-356
Publisher: Lippincott
Grant note: R03 AG053294 / NIA NIH HHS K23 DK105207 / NIDDK NIH HHS R01 AG042504 / NIA NIH HHS K01 AG043501 / NIA NIH HHS R01 AG055781 / NIA NIH HHS R01 AG039449 / NIA NIH HHS R56 AG039449 / NIA NIH HHS K24 DK101828 / NIDDK NIH HHS P30 AG021334 / NIA NIH HHS
Resource Type: Journal article
Language: English
Academic Unit: College of Medicine
Web of Science ID: WOS:000528589800028
Scopus ID: 2-s2.0-85078815640
Other Identifier: 991019335327704721

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Collaboration types: Domestic collaboration
Web of Science research areas: Immunology; Surgery; Transplantation

Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey

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Abstract

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UN Sustainable Development Goals (SDGs)

InCites Highlights

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