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Percutaneous coronary intervention: historical perspectives, current status, and future directions
Journal article   Peer reviewed

Percutaneous coronary intervention: historical perspectives, current status, and future directions

Heidar Arjomand, Zoltan G Turi, Daniel McCormick and Sheldon Goldberg
The American heart journal, v 146(5), pp 787-796
Nov 2003
PMID: 14597926

Abstract

Angioplasty, Balloon, Coronary - adverse effects Angioplasty, Balloon, Coronary - trends Atherectomy Coronary Disease - therapy Coronary Restenosis - etiology Coronary Restenosis - prevention & control Coronary Thrombosis - etiology Coronary Thrombosis - prevention & control Humans Myocardial Infarction - therapy Stents - adverse effects
In the twenty-six years since Gruntzig introduced a simple balloon angioplasty technique, percutaneous coronary intervention has undergone extraordinary growth and has now surpassed bypass surgery in frequency of performance. Several critical breakthrough technologies account for this remarkable progress: intracoronary stents have increased success rates and reduced restenosis, adjunctive antiplatelet therapy has reduced periprocedural complications, and restenosis after stent placement has been effectively treated with local radiation. Most recently, drug-eluting stents coated with cell-cycle inhibitors have shown great promise for further reducing restenosis, possibly to negligible levels.

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Web of Science research areas
Cardiac & Cardiovascular Systems
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