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Journal article
Performance of different exposure assessment approaches in a study of bitumen fume exposure and lung cancer mortality
American journal of industrial medicine, v 43(1)
Jan 2003
PMID: 12494420
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
BACKGROUND: We compared performance of different exposure assessment approaches in a cohort study of cancer risk among European asphalt workers. METHODS: Three bitumen fume exposure indices (duration of exposure (years), average exposure (mg/m3) and cumulative exposure (mg/m3*years)) and two latency models (with and without a 15 year lag) were considered for an association between lung cancer mortality and bitumen fume. RESULTS: There was no association between lung cancer risk and either duration or cumulative exposure. However, there was the suggestion of an increase in lung cancer risk accompanying rise in average exposure. Only models with average bitumen fume exposure (with or without lag) improved model fit, albeit to the same extent. CONCLUSIONS: Constructing quantitative indices of exposure intensity was justified because they produced the greatest improvement in fit of models that explored possible relationship between bitumen fume exposure and lung cancer risk. The identified associations require further investigation.
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Details
- Title
- Performance of different exposure assessment approaches in a study of bitumen fume exposure and lung cancer mortality
- Creators
- Igor Burstyn - Utrecht UniversityPaolo Boffetta - International Agency For Research On CancerTimo Kauppinen - Finnish Institute of Occupational HealthPirjo Heikkilä - Finnish Institute of Occupational HealthOle Svane - Danish Working Environment AuthorityTimo Partanen - Finnish Institute of Occupational HealthIsabelle Stücker - InsermRainer Frentzel-Beyme - Leibniz Institute for Prevention Research and Epidemiology - BIPSWolfgang Ahrens - Leibniz Institute for Prevention Research and Epidemiology - BIPSHiltrud Merzenich - Leibniz Institute for Prevention Research and Epidemiology - BIPSDick Heederik - Utrecht UniversityMariette Hooiveld - Utrecht UniversityBert Brunekreef - Utrecht UniversitySverre Langård - Centre for Occupational and Environmental Medicine, The National Hospital University of Oslo, Oslo, NorwayBritt Randem - Centre for Occupational and Environmental Medicine, The National Hospital University of Oslo, Oslo, NorwayBengt Järvholm - Umeå UniversityIngvar Bergdahl - Umeå UniversityJudith Shaham - Occupational Cancer Unit, Occupational Health and Rehabilitation Institute, Raanana, IsraelGilles Ferro - International Agency For Research On CancerHans Kromhout - Utrecht University
- Publication Details
- American journal of industrial medicine, v 43(1)
- Publisher
- Wiley
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Environmental and Occupational Health
- Web of Science ID
- WOS:000180149100005
- Scopus ID
- 2-s2.0-0037228290
- Other Identifier
- 991019203704404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health