Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

KEYNOTE-671 Investigators; Heather Wakelee; Moishe Liberman; Terufumi Kato; Masahiro Tsuboi; Se-Hoon Lee; Shugeng Gao; Ke-Neng Chen; Christophe Dooms; Margarita Majem; Ekkehard Eigendorff; Gastón L. Martinengo; Olivier Bylicki; Delvys Rodríguez-Abreu; Jamie E. Chaft; Silvia Novello; Jing Yang; Steven M. Keller; Ayman Samkari; Jonathan D. Spicer

doi:10.1056/NEJMoa2302983

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Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

Journal article

Open access

Peer reviewed

Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

KEYNOTE-671 Investigators, Heather Wakelee, Moishe Liberman, Terufumi Kato, Masahiro Tsuboi, Se-Hoon Lee, Shugeng Gao, Ke-Neng Chen, Christophe Dooms, Margarita Majem, …

The New England journal of medicine, v 389(6), pp 491-503

10 Aug 2023

DOI: https://doi.org/10.1056/NEJMoa2302983

PMID: 37272513

Featured in Collection : UN Sustainable Development Goals @ Drexel

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11074923View

Accepted (AM)Open Access (License Unspecified), Open

Abstract

Critical Care General

Pulmonary

Treatments in Oncology

ESI Highly Cited Paper (Incites)

Critical Care

Hematology

Lung Cancer

Oncology

Patients with resectable lung cancer were assigned to neoadjuvant pembrolizumab or placebo plus chemotherapy and adjuvant pembrolizumab or placebo. Two-year event-free survival was 62.4% with pembrolizumab and 40.6% with placebo.

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821 citations in Web of Science

686 citations in Scopus

Details

Title: Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer
Creators: KEYNOTE-671 Investigators (Collaboration)
Heather Wakelee - Stanford University
Moishe Liberman - Centre Hospitalier de l’Université de Montréal
Terufumi Kato - Kanagawa Prefectural Hospital Organization
Masahiro Tsuboi - National Cancer Center Hospital East
Se-Hoon Lee - Sungkyunkwan University
Shugeng Gao - National Clinical Research
Ke-Neng Chen - Peking University
Christophe Dooms - Universitaire Ziekenhuizen Leuven
Margarita Majem - Hospital de Sant Pau
Ekkehard Eigendorff - Zentralklinik Bad Berka
Gastón L. Martinengo
Olivier Bylicki - Hôpital d'Instruction des Armées Sainte-Anne
Delvys Rodríguez-Abreu - Hospital Universitario Insular de Gran Canaria
Jamie E. Chaft - Memorial Sloan Kettering Cancer Center
Silvia Novello - Ospedale San Luigi Gonzaga
Jing Yang - Merck Institute for Science Education
Steven M. Keller - Merck Institute for Science Education
Ayman Samkari - Merck Institute for Science Education
Jonathan D. Spicer - McGill University Health Centre
Publication Details: The New England journal of medicine, v 389(6), pp 491-503
Publisher: Massachusetts Medical Society
Resource Type: Journal article
Language: English
Academic Unit: Pediatrics
Web of Science ID: WOS:001000472100001
Scopus ID: 2-s2.0-85166308111
Other Identifier: 991021838278204721

UN Sustainable Development Goals (SDGs)

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Highly Cited Paper

Collaboration types: Industry collaboration; Domestic collaboration; International collaboration
Web of Science research areas: Oncology

Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

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Abstract

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Details

UN Sustainable Development Goals (SDGs)

InCites Highlights

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