Journal article
Periventricular white matter alterations, dementia, and binswanger's disease
Developmental neuropsychology, v 9(2), pp 87-102
01 Apr 1993
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Although periventricular white matter alterations (PWMA) are commonly reported on magnetic resonance imaging (MRI) scans of elderly individuals, a consistent pattern of neuropsychological deficits has yet to be found. However, there are some findings suggesting that executive functions (Luria, 1980) are more impaired than other areas of neuropsychological functioning. We undertook a prospective study of two groups of elderly, demented patients with and without PWMA as measured by MRI. The results demonstrated that subjects with greater white matter alterations performed worse on some executive function tests (e.g., Trail Making Test-Part B and competing programs/go-no-go), whereas there were no differences in other areas of neuropsychological functioning. There were no between-group differences on the Modified Ischemic Scale (Rosen, Terry, Fuld, Katzman, & Peck, 1980) or on measures of depression. Other pertinent clinical and methodological issues related to the clinical presentation of PWMA, as well as Binswanger's disease, are discussed.
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Details
- Title
- Periventricular white matter alterations, dementia, and binswanger's disease
- Creators
- David J. Libon - Crozer-Keystone Health SystemRodney A. Swenson - Merit Care Neuwscience CenterBarbara L. Malamut - Philadelphia Fire DepartmentMary Scanlon - Einstein Medical Center PhiladelphiaH. Branch Coslett - Temple UniversityLaura Prouty Sands - York College of Pennsylvania
- Publication Details
- Developmental neuropsychology, v 9(2), pp 87-102
- Publisher
- Taylor & Francis Group
- Number of pages
- 16
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:A1993MQ26100002
- Scopus ID
- 2-s2.0-0002329951
- Other Identifier
- 991021901313304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology
- Psychology, Developmental
- Psychology, Experimental