Journal article
Peromyscus transcriptomics: Understanding adaptation and gene expression plasticity within and between species of deer mice
Seminars in cell & developmental biology, v 61, pp 131-139
01 Jan 2017
PMID: 27531052
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Deer mice in the genus Peromyscus occupy nearly every terrestrial habitat in North America, and have a long history as subjects of behavioral, ecological, evolutionary, and physiological study. Recent advances in transcriptomics, the study of the complete set of RNA transcripts produced by certain cell types or under certain conditions, have contributed to the development of Peromyscus as a model system. We review the recent use of transcriptomics to investigate how natural selection and gene expression plasticity contribute to the existence of deer mice in challenging environments such as highlands, deserts, and cities across North America. Transcriptomics also holds great promise for elucidating the genetic basis of mating systems and other behaviors in Peromyscus, but has to date been underutilized for developmental biology and disease studies. Future Peromyscus studies should apply robust comparative frameworks to analyze the transcriptomics of multiple populations of the same species across varying environmental conditions, as well as multiple species that vary in traits of interest. (C) 2016 Elsevier Ltd. All rights reserved.
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Details
- Title
- Peromyscus transcriptomics: Understanding adaptation and gene expression plasticity within and between species of deer mice
- Creators
- Jason Munshi-South - Fordham UniversityJonathan L. Richardson - Providence College
- Publication Details
- Seminars in cell & developmental biology, v 61, pp 131-139
- Publisher
- Elsevier
- Number of pages
- 9
- Grant note
- R15GM099055 / National Institute of General Medical Sciences of the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of General Medical Sciences (NIGMS) DEB 1457523 / National Science Foundation; National Science Foundation (NSF)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biodiversity, Earth, and Environmental Science (BEES)
- Web of Science ID
- WOS:000391837800017
- Scopus ID
- 2-s2.0-84995471852
- Other Identifier
- 991021903954504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cell Biology
- Developmental Biology