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Persistence of Hypsarrhythmia in Children Beyond the Age of Three Years
Journal article   Peer reviewed

Persistence of Hypsarrhythmia in Children Beyond the Age of Three Years

Kandan Kulandaivel, Divya S. Khurana, Karen S. Carvalho, Joseph J. Melvin, Agustin Legido and Ignacio Valencia
Journal of child neurology, v 26(7), pp 835-837
01 Jul 2011
DOI: https://doi.org/10.1177/0883073810394849
PMID: 21464235
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Clinical Neurology Life Sciences & Biomedicine Neurosciences & Neurology Pediatrics Science & Technology
Occurrence of hypsarrhythmia after the age of 3 years is rare. The objective of this study is to describe a group of patients who have persistence of hypsarrhythmia after the age of 3 years. The authors retrospectively reviewed the EEGs of 24 patients with hypsarrhythmia. Electroencephalographies (EEGs) were scored using a hypsarrhythmia scale. The clinical data of 7 patients with EEG scores greater than 9 at ages >= 3 years were analyzed. The mean age was 5.7 years (range, 3-8.7 years). EEG background amplitudes ranged from 200 to 500 mu V in 5 patients and it was greater than 500 mu V in the other 2. Six patients had electrodecremental responses. The etiology was developmental in 3 patients, mitochondrial disease in 2, and hypoxic ischemic encephalopathy in 2. Our study suggests that a subgroup of patients with hypsarrhythmia may not transition to a Lennox-Gastaut pattern or normalization after the age of 3 years.

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2 citations in Web of Science
2 citations in Scopus

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UN Sustainable Development Goals (SDGs)

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#3 Good Health and Well-Being

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Web of Science research areas
Clinical Neurology
Pediatrics
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