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Pertussis in the Era of New Strains of Bordetella pertussis
Journal article   Peer reviewed

Pertussis in the Era of New Strains of Bordetella pertussis

Emily Souder and Sarah S Long
Infectious disease clinics of North America, v 29(4), pp 699-713
Dec 2015
PMID: 26337739

Abstract

Adolescent Bordetella pertussis - classification Bordetella pertussis - immunology Child Child, Preschool Disease Outbreaks Female Humans Incidence Infant Pertussis Vaccine - administration & dosage Pertussis Vaccine - immunology Pregnancy Prevalence United States - epidemiology Vaccination Whooping Cough - epidemiology Whooping Cough - immunology Whooping Cough - microbiology Whooping Cough - prevention & control Young Adult
Despite implementation of a successful vaccination program, pertussis remains a significant health problem. Although the incidence of pertussis in the United States is reduced by approximately 80% compared with incidence before the introduction of vaccination in the 1940s, deaths still occur and the unrecognized disease burden remains high, with 1 million Bordetella pertussis infections annually in the United States estimated by serologic surveys. Reasons for the resurgence and current prevalence of pertussis may be multifactorial and include waning vaccine-induced protection as well as lower vaccine effectiveness, failure to vaccinate, and changes in the organism itself.

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Web of Science research areas
Immunology
Infectious Diseases
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