Life Sciences & Biomedicine Science & Technology Surgery Transplantation
Purpose of Review Low physical function (PF) is common among individuals with end-stage kidney disease. In this review, we explore data on the impacts of PF on access to kidney transplantation (KT) and KT outcomes. We also discuss the latest interventions to improve PF in pre- and post-KT settings. Recent Findings Many US KT programs measure PF or related constructs when assessing KT candidacy. Although carefully selected KT candidates with low PF can benefit from KT with respect to survival and quality of life, low PF decreases the likelihood of being listed for KT and increases the risk of adverse post-KT outcomes. Recent trials suggest that exercise is a promising strategy to improve PF among KT candidates and recipients. Low PF is a potentially modifiable risk factor for adverse pre- and post-KT outcomes. Research is needed to determine the ideal PF metric for use in KT evaluations and interventions to improve PF.
Physical Function in Kidney Transplantation: Current Knowledge and Future Directions
Creators
Dia Yang - Drexel University
Lucy Robinson - Drexel University
Christian Selinski - Drexel University
Thalia Bajakian - Drexel University
Christina Mejia - Thomas Jefferson University
Meera Nair Harhay - Drexel University
Publication Details
Current transplantation reports, v 7(2), pp 46-55
Publisher
Springer Nature
Number of pages
10
Grant note
Commonwealth Universal Research Enhancement Grant
K23DK105207 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
Resource Type
Journal article
Language
English
Academic Unit
College of Medicine; Epidemiology and Biostatistics
Web of Science ID
WOS:000705322500003
Scopus ID
2-s2.0-85090085098
Other Identifier
991019168194404721
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