Journal article
Pilot study to evaluate a plasma device for the treatment of onychomycosis
Clinical and experimental dermatology, v 42(3), pp 295-298
Apr 2017
PMID: 28188648
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Onychomycosis is a fungal infection of the nail unit, and is the most common of the nail disorders. Current therapies for onychomycosis have less than ideal efficacy and have the potential for adverse effects. As previous studies have shown that nonthermal plasma inhibits the in vitro growth of Trichophyton rubrum, we conducted a pilot study on 19 participants with toenail onychomycosis. The primary endpoint was safety of the device, and secondary outcome measures were clinical efficacy and mycological cure. Patient satisfaction was measured using questionnaires at the completion of the study. All but one patient met the primary endpoint of safety and there were no long-term sequelae. The overall clinical cure was 53.8% and the mycological cure was 15.4%. The majority of patients were satisfied with the treatment. Our conclusions are that nonthermal plasma is a safe treatment and may have a beneficial effect on toenail onychomycosis.
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Details
- Title
- Pilot study to evaluate a plasma device for the treatment of onychomycosis
- Creators
- S R Lipner - Cornell UniversityG Friedman - Drexel UniversityR K Scher - Cornell University
- Publication Details
- Clinical and experimental dermatology, v 42(3), pp 295-298
- Publisher
- Wiley
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Electrical and Computer Engineering
- Web of Science ID
- WOS:000396829600008
- Scopus ID
- 2-s2.0-85012168837
- Other Identifier
- 991019169904504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Dermatology