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Plasticity of Muscle Architecture After Supraspinatus Tears
Journal article   Open access   Peer reviewed

Plasticity of Muscle Architecture After Supraspinatus Tears

Samuel R. Ward, Joseph J. Sarver, Carolyn M. Eng, Alan Kwan, Carola C. Wurgler-Hauri, Stephanie M. Perry, Gerald R. Williams, Louis J. Soslowsky and Richard L. Lieber
The journal of orthopaedic and sports physical therapy, v 40(11), pp 729-735
01 Nov 2010
DOI: https://doi.org/10.2519/jospt.2010.3279
PMID: 20710096
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://europepmc.org/articles/pmc4321894View
Accepted (AM) Open Open Access (License Unspecified)

Abstract

Life Sciences & Biomedicine Orthopedics Rehabilitation Science & Technology Sport Sciences
STUDY DESIGN Controlled laboratory study OBJECTIVES To measure the architectural properties of rat supraspinatus muscle after a complete detachment of its distal tendon METHODS Supraspinatus muscles were released from the left humerus of 29 Sprague Dawley rats (mass 400 450 g) and the animals were returned to cage activity for 2 weeks (n = 12) 4 weeks (n = 9) or 9 weeks (n = 8) before euthanasia Measurements of muscle mass perination angle fiber bundle length (sarcomere number) and sarcomere length permitted calculation of normalized fiber length serial sarcomere number and physiological cross sectional area RESULTS Coronal oblique sections of the supraspinatus confirmed surgical transection of the supraspinatus muscle at 2 weeks with reattachment by 4 weeks Muscle mass and length were significantly lower in released muscles at 2 weeks 4 weeks and 9 weeks Sarcomere lengths in released muscles were significantly shorter at 2 weeks but not different by 4 weeks Sarcomere number was significantly reduced at 2 and 4 weeks but returned to control values by 9 weeks The opposing effects of smaller mass and shorter fibers produced significantly smaller physiological cross sectional area at 2 weeks but physiological cross sectional area returned to control levels by 4 weeks CONCLUSIONS Release of the supraspinatus muscle produced early radial and longitudinal atrophy of the muscle The functional implications of these adaptations would be most profound at early time points (particularly relevant for rehabilitation) when the muscle remains smaller in cross sectional area and due to reduced sarcomere number would be forced to operate over a wider range of the length tension curve and at higher velocities all adaptations resulting in compromised force generating capacity These data are relevant to physical therapy because they provide tissue level insights into impaired muscle and shoulder function following rotator cuff injury J Orthop Sports Phys Ther 2010 40(11) 729 735 doi 10.2519/jospt.2010.3279

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51 citations in Web of Science
51 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Orthopedics
Rehabilitation
Sport Sciences
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