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Published, Version of Record (VoR)CC BY-NC-SA V4.0, Open
Journal article
Plastics and carcinogenesis: The example of vinyl chloride
Journal of carcinogenesis, v 11(1), pp 5-5
12 Mar 2012
PMID: 22529741
Abstract
The manufacture, use and disposal of various plastics can pose numerous health risks, including the risk of cancer. A model example of carcinogenic risk from plastics is provided by polyvinyl chloride, since it is composed of the known human carcinogen vinyl chloride (VC). In recent years, much has been learned about the molecular biological pathways of VC carcinogenesis. This has led to molecular epidemiologic studies of VC carcinogenesis in exposed human populations which have identified useful biomarkers of exposure, effect and susceptibility for VC. These studies have in turn provided the basis for new molecular approaches for the prevention and treatment of VC cancers. This model could have much wider applicability for many other carcinogenic exposures and many other human cancers.
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53 citations in Scopus
Details
- Title
- Plastics and carcinogenesis: The example of vinyl chloride
- Creators
- Paul Wesley Brandt-Rauf - University of Illinois ChicagoYongliang Li - University of Illinois at ChicagoChangmin Long - University of Illinois at ChicagoRegina Monaco - University of Illinois at ChicagoGopala Kovvali - Rutgers, The State University of New JerseyMarie-Jeanne Marion - Unite 871, Institut National del la Sante et de la Recherche Medicale, Lyon, France
- Publication Details
- Journal of carcinogenesis, v 11(1), pp 5-5
- Publisher
- Medknow Publications & Media Pvt Ltd
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Scopus ID
- 2-s2.0-84872690647
- Other Identifier
- 991019176647604721