Journal article
Point-of-Care Molecular Test for Zika Infection
Clinical laboratory international, v 41, pp 25-27
Jun 2017
PMID: 28819345
Abstract
The recent outbreak of Zika virus (ZIKV) infection has led to a serious threat to public health. Rapid and sensitive diagnostics for ZIKV infection are crucial because Zika infection is usually mild and often asymptomatic, but may have serious consequences to infants born to infected mothers. We report on a simple, sensitive, inexpensive, point-of-care (POC) diagnostic technology for rapid detection of ZIKV in saliva. We use a chemically heated cup for isothermal amplification without a need for electrical power. The detection results can be directly read out by eye.
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Details
- Title
- Point-of-Care Molecular Test for Zika Infection
- Creators
- Michael G Mauk - University of PennsylvaniaJinzhao Song - University of PennsylvaniaHaim H Bau - University of PennsylvaniaChangchun Liu - University of Pennsylvania
- Publication Details
- Clinical laboratory international, v 41, pp 25-27
- Grant note
- K25 AI099160 / NIAID NIH HHS R01 CA214072 / NCI NIH HHS R21 DE026700 / NIDCR NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Engineering Leadership and Society/Engineering Technology
- Other Identifier
- 991020623758604721