Journal article
Poor prognosis associated with thrombocytosis in patients with cervical cancer
Cancer, v 69(12), pp 2975-2977
15 Jun 1992
PMID: 1591690
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The medical records of 113 patients treated with radiation therapy for invasive cervical cancer between 1975 and 1985 were retrospectively reviewed. Patients with thrombocytosis (platelet count > 400,000/μ1) were compared with those with normal platelet counts. Thrombo‐cytosis was present at the initiation of therapy in 20 (17.7%) of the 113 patients. The 5‐year cumulative survival rate for the 93 patients with normal platelet counts was 65%, whereas it was 25% for the 20 with thrombocytosis (P < 0.0001, log‐rank test). Using Cox's proportional hazards model, thrombocytosis continued to correlate strongly with poor survival even when adjusted for histo‐logic type, patient age, and disease stage (P < 0.001). Thrombocytosis is an independent indicator of poor prognosis in patients with cervical cancer.
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Details
- Title
- Poor prognosis associated with thrombocytosis in patients with cervical cancer
- Creators
- Enrique HernandezMarc LavineCharles J DuntonEdward GracelyJanet Parker
- Publication Details
- Cancer, v 69(12), pp 2975-2977
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; New York
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- MD (Doctor of Medicine) Program
- Web of Science ID
- WOS:A1992HX30600017
- Scopus ID
- 2-s2.0-0026717722
- Other Identifier
- 991014878475204721
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- Web of Science research areas
- Oncology