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Porous Crystalsomes via Emulsion Crystallization and Polymer Phase Separation
Journal article

Porous Crystalsomes via Emulsion Crystallization and Polymer Phase Separation

Mark C. Staub, Seyong Kim, Shichen Yu, Christopher Y. Li and Seung-Lae Kim
ACS macro letters, v 11(8), pp 1022-1027
16 Aug 2022

Abstract

Crystalsomes are crystalline capsules that are formed by controlling polymer crystallization to break translational symmetry. While recent studies showed that these crystalline capsules exhibit interesting mechanical properties, thermal behavior, and excellent performance in blood circulation, the closed capsule is undesired for drug delivery applications. We report the formation and characterization of porous crystalsomes where porosity is rendered on the crystalline shells. A miniemulsion is formed using two amphiphilic block copolymers (BCP). The competition between controlled crystallization and phase separation of the BCPs at the emulsion surface leads to multiphase crystalsomes. Subsequently removing one BCP produces porous crystalline capsules.

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Polymer Science
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