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Journal article
Positive acute viral infection markers, autoimmune disease and type II mixed cryoglobulinemia: a rare concurrence
BMJ case reports, v 12(11), e230492
28 Nov 2019
PMID: 31780611
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Cryoglobulins are abnormal serum immunoglobulins that tend to precipitate in intravascular compartments at temperatures lower than 37°C causing blood flow restriction to vital organs. They are divided into type I, II and III based on the immunoglobulin subtypes of the cryoprecipitates. Type II cryoglobulinemia is most commonly associated with viral infections, autoimmune diseases and lymphoproliferative disorders. Here, we reported an 80-year-old man who presented with fatigue, acute kidney injury, palpable purpura, anaemia and altered mental status. He was diagnosed with type II cryoglobulinemia with concomitant positive autoimmune markers, varicella IgM antibody and IgM hepatitis B core antibody. The patient responded well to intravenous and oral steroid treatment.
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Details
- Title
- Positive acute viral infection markers, autoimmune disease and type II mixed cryoglobulinemia: a rare concurrence
- Creators
- Kehua Zhou - University at Buffalo, State University of New YorkShumaila Muhammad Iqbal - University at Buffalo, State University of New YorkAli Alameri - University at Buffalo, State University of New YorkCassandra Zhi - Drexel University College of Medicine, Philadelphia, PA, USAAmmad Naeem - University at Buffalo, State University of New York
- Publication Details
- BMJ case reports, v 12(11), e230492
- Publisher
- British Medical Journal (BMJ)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000661454700036
- Scopus ID
- 2-s2.0-85075802904
- Other Identifier
- 991021860695504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Medicine, General & Internal