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Postoperative pelvic irradiation of stage II ovarian carcinoma
Journal article   Peer reviewed

Postoperative pelvic irradiation of stage II ovarian carcinoma

Paul E. Wallner, Luther W. Brady, George C. Lewis and Robert C. Nuss
International journal of radiation oncology, biology, physics, v 2(3), pp 281-288
Mar 1977
DOI: https://doi.org/10.1016/0360-3016(77)90086-4
PMID: 193810
url
https://doi.org/10.1016/0360-3016(77)90086-4View
Published, Version of Record (VoR) Restricted

Abstract

Ovarian carcinoma Pelvic irradiation Postoperative irradiation Radiation therapy Stage II ovarian carcinoma
Clinical Stage II carcinoma of the ovary (1964 FIGO classification) represents a small proportion of total patients and has not been studied extensively. Even though the disease apparently is localized, end-results have been poor. Between 1960 and 1970, 24 patients with clinical Stage II disease received postoperative megavoltage pelvic irradiation following surgical procedures of varying extent. All patients but one received between 5000 and 6000 rad tumor dose to the whole pelvis and all patients were evaluable at a minimum of 5 years. Of 4 Stage II-A patients one was alive without disease. No patients were alive with recurrent tumor. Recurrences in the pelvis occurred only in 2 patients; 4 patients had recurrent disease in the pelvis and upper abdomen. A total of 8 patients developed upper abdominal recurrences in the apparent absence of pelvic disease. These results and those of others which are discussed in this paper suggest that surgery and irradiation to the pelvis only will not eradicate disease completely in over 60% of patients with clinical Stage II ovarian carcinoma.

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