Journal article
Poststroke Fractures in A Bi-ethnic Community
Journal of stroke and cerebrovascular diseases, v 21(6), pp 471-477
Aug 2012
PMID: 21334222
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Mexican Americans have increased risks of stroke and lower fractures compared with non-Hispanic whites, but little is known about poststroke fracture risk in Mexican Americans. The objective of this study was to describe poststroke fracture risk in a bi-ethnic population and to compare risk by ethnicity.
In the Brain Attack Surveillance in Corpus Christi Project, strokes were identified through hospital surveillance (2000-2004) and validated by neurologists (n = 2389). Inpatient claims for fractures were ascertained (2000-2004) and cross-referenced with strokes. Survival free from fracture (any and hip) poststroke was estimated and compared by ethnicity. Cox regression was used to test the association of ethnicity and fracture risk adjusted for confounders. Interaction terms for ethnicity and age were considered.
The mean age was 71 years (SD, 13 yrs); 54% were Mexican American and 52% were women. The mean follow-up was 4 years. There were 105 fractures (33% of the hips). Survival free of any fracture and of hip fracture did not differ by ethnicity. Increasing age, female gender, intracerebral hemorrhage, and greater stroke severity were associated with risk of any fracture, but ethnicity was not. Ethnicity was associated with risk of hip fracture, but this association was modified by age (P = .02), where Mexican Americans were protected from hip fractures at younger but not older ages.
Stroke patients were at high risk for fractures, with a 10% risk at 5 years. Mexican Americans were protected from hip fractures at younger but not older ages. Both elderly Mexican Americans and non-Hispanic whites should be targeted for poststroke fracture prevention.
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Details
- Title
- Poststroke Fractures in A Bi-ethnic Community
- Creators
- Lynda D Lisabeth - Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MichiganLewis B Morgenstern - Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MichiganJeffrey J Wing - Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MichiganBrisa N Sanchez - Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MichiganDarin B Zahuranec - Stroke Program, University of Michigan Medical School, Ann Arbor, MichiganLesli E Skolarus - Stroke Program, University of Michigan Medical School, Ann Arbor, MichiganJames F Burke - Stroke Program, University of Michigan Medical School, Ann Arbor, MichiganMichael Kleerekoper - St. Joe’s Mercy Hospital, Ann Arbor, MichiganMelinda A Smith - Stroke Program, University of Michigan Medical School, Ann Arbor, MichiganDevin L Brown - Stroke Program, University of Michigan Medical School, Ann Arbor, Michigan
- Publication Details
- Journal of stroke and cerebrovascular diseases, v 21(6), pp 471-477
- Publisher
- Elsevier
- Grant note
- R01 NS38916 / National Institute of Neurological Disorders and Stroke
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000306656600007
- Scopus ID
- 2-s2.0-84864144281
- Other Identifier
- 991014878010404721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neurosciences
- Peripheral Vascular Disease