Journal article
Predictive accuracy of ST depression during rapid atrial fibrillation on the presence of obstructive coronary artery disease
The American journal of emergency medicine, v 30(7), pp 1042-1047
01 Sep 2012
PMID: 21855255
Abstract
Rapid atrial fibrillation (AF) is commonly associated with ST-segment depressions. ST-segment depression during a chest pain episode or exercise stress testing in sinus rhythm is predictive of obstructive coronary artery disease (CAD), but it is unclear if the presence or magnitude of ST-segment depression during rapid AF has similar predictive accuracy.
One hundred twenty-seven patients with rapid AF (heart rate ≥120 beats per minute) who had cardiac catheterization performed during the same hospital admission were retrospectively reviewed. Variables to compute thrombolysis in myocardial infarction (TIMI) risk score, demographic profiles, ST-segment deviation, cardiac catheterization results, and cardiac interventions were collected.
Thirty-five patients had ST-segment depression of 1 mm or more, and 92 had no or less than 1 mm ST depression. Thirty-one patients were found to have obstructive CAD. In the group with ST-segment depression, 11 (31%) patients had obstructive CAD and 24 (69%) did not. In the group with less than 1 mm ST-segment depression, 20 (22%) had obstructive CAD and 72 (78%) did not (P = .25). Sensitivity, specificity, and positive and negative predictive values for presence of obstructive CAD were 35%, 75%, 31%, and 78%, respectively. The presence of ST-segment depression of 1 mm or more was not associated with presence of obstructive CAD before or after adjustment of TIMI variables. The relationship between increasing grades of ST-segment depression and obstructive CAD showed a trend toward significance (P = .09), which did not persist after adjusting for TIMI risk variables (P = .36).
ST-segment depression during rapid AF is not predictive for the presence of obstructive CAD.
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Details
- Title
- Predictive accuracy of ST depression during rapid atrial fibrillation on the presence of obstructive coronary artery disease
- Creators
- Rajesh Pradhan - Thomas Jefferson University HospitalAshok Chaudhary - Reading HospitalAnthony A. Donato (Corresponding Author) - Reading Hospital
- Publication Details
- The American journal of emergency medicine, v 30(7), pp 1042-1047
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate); General Internal Medicine
- Web of Science ID
- WOS:000308541100004
- Scopus ID
- 2-s2.0-84865462552
- Other Identifier
- 991022161735004721