Journal article
Predictors of attrition and weight loss success: Results from a randomized controlled trial
Behaviour research and therapy, v 47(8), pp 685-691
2009
PMID: 19497559
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Attrition is a common problem in weight loss trials. The present analysis examined several baseline and early-treatment process variables, as predictors of attrition and outcome in a clinical trial that combined pharmacotherapy and behavior therapy for weight loss. Participants were 224 obese adults who were treated with sibutramine alone, lifestyle modification alone, combined therapy, or sibutramine plus brief lifestyle modification. Predictors included baseline characteristics (e.g., demographic, weight-related, psychological, and consumption-related variables), plus attendance, adherence, and weight loss in the early weeks of treatment. Outcomes were attrition and weight loss success (i.e., ≥5% reduction in body weight) at 1 year. Multivariable models, adjusting for other relevant variables, found that younger age and greater baseline depressive symptoms were related to increased odds of attrition (
ps ≤ 0.003). Greater early weight loss marginally reduced the odds of attrition (
p = 0.06). Predictors of weight loss success at 1 year were Caucasian ethnicity (
p = 0.04), lower baseline depressive symptoms (
p = 0.04), and weight loss during the first 3 weeks of treatment (
p < 0.001). Thus, depressive symptoms at baseline were a significant predictor of both attrition and weight loss success. As a process variable, early weight loss appears to have more predictive value than early attendance at treatment sessions or early adherence.
Metrics
Details
- Title
- Predictors of attrition and weight loss success: Results from a randomized controlled trial
- Creators
- Anthony N Fabricatore - University of Pennsylvania School of Medicine, 3535 Market Street, Ste. 3108, Philadelphia, PA 19104-3309, United StatesThomas A Wadden - University of Pennsylvania School of Medicine, 3535 Market Street, Ste. 3108, Philadelphia, PA 19104-3309, United StatesReneé H Moore - University of Pennsylvania School of Medicine, 3535 Market Street, Ste. 3108, Philadelphia, PA 19104-3309, United StatesMeghan L Butryn - Drexel University, United StatesSteven B Heymsfield - Merck Research Laboratories, United StatesAllison Martin Nguyen - Merck Research Laboratories, United States
- Publication Details
- Behaviour research and therapy, v 47(8), pp 685-691
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics; Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
- Web of Science ID
- WOS:000268616000007
- Scopus ID
- 2-s2.0-67650177052
- Other Identifier
- 991014878234304721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology, Clinical