Journal article
Preferences for Prophylactic Oral Antibiotic Use in Dermatologic Surgery: A Multicenter Discrete Choice Experiment
Dermatologic surgery, v 47(9), pp 1214-1219
01 Sep 2021
PMID: 34081047
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Antibiotics are often prescribed after dermatologic surgery for infection prophylaxis, but patient preferences about prophylactic antibiotics are not well understood.
To understand patient preferences about taking antibiotics to prevent surgical site infection (SSI) relative to antibiotic efficacy and antibiotic-associated adverse drug reactions.
Multi-center, prospective discrete choice experiment (DCE).
Three hundred thirty-eight respondents completed the survey and DCE. 54.8% of respondents preferred to take an antibiotic if it reduced the SSI rate from 5% to 2.5% and if the risk of adverse drug reactions was low (1% risk gastrointestinal upset, 0.5% risk itchy skin rash, 0.01% risk emergency department visit). Even if an antibiotic could eliminate SSI risk (0% risk SSI) and had a low adverse drug reaction profile, 26.7% of respondents prefer not to take prophylactic oral antibiotics.
Risk-benefit thresholds for taking antibiotics to prevent SSI vary widely. Clinical trials are needed to better characterize the effectiveness and risks of oral antibiotic SSI prophylaxis to guide decision-making. Future studies should also evaluate whether shared decision-making can improve the patient experience.
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Details
- Title
- Preferences for Prophylactic Oral Antibiotic Use in Dermatologic Surgery: A Multicenter Discrete Choice Experiment
- Creators
- Leora Aizman - George Washington UniversityJohn S Barbieri - University of PennsylvaniaElea M Feit - Drexel UniversityTess M Lukowiak - Drexel UniversityAllison M Perz - Rowan UniversityThuzar M Shin - University of PennsylvaniaChristopher J Miller - University of PennsylvaniaNicholas Golda - University of MissouriJustin J Leitenberger - Oregon Health & Science UniversityDavid R Carr - The Ohio State UniversityRajiv I Nijhawan - The University of Texas Southwestern Medical CenterAliza Hasan - University of California, DavisDaniel B Eisen - University of California, DavisJeremy R Etzkorn - University of Pennsylvania
- Publication Details
- Dermatologic surgery, v 47(9), pp 1214-1219
- Publisher
- Lippincott
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Marketing
- Web of Science ID
- WOS:000711691100006
- Scopus ID
- 2-s2.0-85115440678
- Other Identifier
- 991019201217804721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Dermatology
- Surgery