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Journal article
Prefrontal cortex activation by binge-eating status in individuals with obesity while attempting to reappraise responses to food using functional near infrared spectroscopy
Eating and weight disorders, v 28(1), 34
30 Mar 2023
PMID: 36995567
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose
Difficulty reappraising drives to consume palatable foods may promote poorer inhibition and binge eating (BE) in adults with obesity, but neural underpinnings of food-related reappraisal are underexamined.
Methods
To examine neural correlates of food-related reappraisal, adults with obesity with and without BE wore a portable neuroimaging tool, functional near-infrared spectroscopy (fNIRS). fNIRS measured activity in the prefrontal cortex while participants watched videos of food and attempt to “resist” the food stimuli (i.e., “consider the negative consequences of eating the food”).
Results
Participants (N = 32, 62.5% female; BMI 38.6 ± 7.1; 43.5 ± 13.4 y) had a BMI > 30 kg/m2. Eighteen adults (67.0% female; BMI 38.2 ±
7.6) reported BE (≥ 12 BE-episodes in preceding 3 months). The control group comprised 14 adults who denied BE (64.0% female; BMI 39.2 ± 6.6). Among the entire sample, mixed models showed significant, small hyperactivation during crave and resist compared to watch (relax) condition bilaterally in the medial superior frontal gyrus, dorsolateral areas, and middle frontal gyrus (optodes 5, 7, 9, 10, 11, and 12) in the total sample. No statistically significant differences in neural activation were observed between the BE and control group. Moreover, there were no significant group by condition interactions on neural activation.
Conclusion
Among adults with obesity, BE status was not linked to differential activation in inhibitory prefrontal cortex areas during a food-related reappraisal task. Future research is needed with larger samples, adults without obesity, and inhibition paradigms with both behavioral and cognitive components.
Metrics
Details
- Title
- Prefrontal cortex activation by binge-eating status in individuals with obesity while attempting to reappraise responses to food using functional near infrared spectroscopy
- Creators
- Megan N. Parker - Drexel UniversityHelen Burton Murray - Drexel UniversityAmani D. Piers - Drexel UniversityAlexandra Muratore - Drexel UniversityMichael R. Lowe - Drexel UniversityStephanie M. Manasse - Drexel UniversityHasan Ayaz - Drexel UniversityAdrienne S. Juarascio - Drexel University
- Publication Details
- Eating and weight disorders, v 28(1), 34
- Publisher
- Springer International Publishing
- Number of pages
- 8
- Grant note
- K23DK124514 / National Institute of Diabetes and Digestive and Kidney Diseases (http://dx.doi.org/10.13039/100000062) Student Research Grant / Academy for Eating Disorders (http://dx.doi.org/10.13039/100013579) K23 MH105680 / National Institute of Mental Health (http://dx.doi.org/10.13039/100000025)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology); Drexel Solutions Institute; College of Arts and Sciences; School of Biomedical Engineering, Science, and Health Systems; Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
- Web of Science ID
- WOS:000961047500002
- Scopus ID
- 2-s2.0-85151573466
- Other Identifier
- 991020262643404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychiatry