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Preliminary evaluation of dual wavelength phased array imaging on neonatal brain function
Journal article   Open access   Peer reviewed

Preliminary evaluation of dual wavelength phased array imaging on neonatal brain function

Yu Chen, Shuoming Zhou, Chunhua Xie, Shoko Nioka, Maria Delivoria-Papadopoulos, Endla Anday and Britton Chance
Journal of Biomedical Optics, v 5(2)
Apr 2000
PMID: 10938783
url
https://doi.org/10.1117/1.429986View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

functional brain imaging neonate noninvasive diagnosis optical imaging phased array
Imaging of human tissue using noninvasive techniques has been of great interest in biomedical fields. Optical imaging has attracted a lot of attention because of its portability and economy. The possibility that a highly portable, fast, safe, and affordable imaging system which could obtain interpretable images of brain function for pre- and full-term neonates in a few seconds, has been explored in this article. We have used a sensitive optical topography system, termed phased array, in which a pair of equal-amplitude and antiphase light sources are applied to generate a sharp amplitude null and phase transition plane. This two-wavelength (750 and 830 nm), frequency encoded (50 and 52 MHz) phased array imaging system can indicate the blood concentration and oxygenation changes in blood model studies and during parietal brain activation in neonates. Significant functional responses, particularly to parietal stimulation in normal and pathological states of neonatal brain, have been revealed in our study. The preliminary clinical results are presented in this article. ©

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Collaboration types
Domestic collaboration
Web of Science research areas
Biochemical Research Methods
Optics
Radiology, Nuclear Medicine & Medical Imaging
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