Journal article
Prenatal diagnosis of fetal aneuploidies: post-genomic developments
Genome medicine, v 2(8), pp 50-50
05 Aug 2010
PMID: 20687900
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Prenatal diagnosis of fetal aneuploidies and chromosomal anomalies is likely to undergo a profound change in the near future. On the one hand this is mediated by new technical developments, such as chromosomal microarrays, which allow a much more precise delineation of minute sub-microscopic chromosomal aberrancies than the classical G-band karyotype. This will be of particular interest when investigating pregnancies at risk of unexplained development delay, intellectual disability or certain forms of autism. On the other hand, great strides have been made in the non-invasive determination of fetal genetic traits, largely through the analysis of cell-free fetal nucleic acids. It is hoped that, with the assistance of cutting-edge tools such as digital PCR or next generation sequencing, the long elusive goal of non-invasive prenatal diagnosis for fetal aneuploidies can finally be attained.
Metrics
Details
- Title
- Prenatal diagnosis of fetal aneuploidies: post-genomic developments
- Creators
- Sinuhe Hahn - University Hospital of BaselLaird G Jackson - Drexel UniversityBernhard G Zimmermann - Fluidigm (United States)
- Publication Details
- Genome medicine, v 2(8), pp 50-50
- Publisher
- BioMed Central
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000208627100050
- Scopus ID
- 2-s2.0-78751687893
- Other Identifier
- 991019350670004721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Industry collaboration
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Genetics & Heredity