Journal article
Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain
Epidemiology (Cambridge, Mass.), v 26(1), pp 43-50
Jan 2015
PMID: 25437317
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Prenatal air pollution exposure inhibits fetal growth, but implications for postnatal growth are unknown.
We assessed weights and lengths of US infants in the Project Viva cohort at birth and 6 months. We estimated 3rd-trimester residential air pollution exposures using spatiotemporal models. We estimated neighborhood traffic density and roadway proximity at birth address using geographic information systems. We performed linear and logistic regression adjusted for sociodemographic variables, fetal growth, and gestational age at birth.
Mean birth weight-for-gestational age z-score (fetal growth) was 0.17 (standard deviation [SD] = 0.97; n = 2,114), 0- to 6-month weight-for-length gain was 0.23 z-units (SD = 1.11; n = 689), and 17% had weight-for-length ≥95th percentile at 6 months of age. Infants exposed to the highest (vs. lowest) quartile of neighborhood traffic density had lower fetal growth (-0.13 units [95% confidence interval (CI) = -0.25 to -0.01]), more rapid 0- to 6-month weight-for-length gain (0.25 units [95% CI = 0.01 to 0.49]), and higher odds of weight-for-length ≥95th percentile at 6 months (1.84 [95% CI = 1.11 to 3.05]). Neighborhood traffic density was additionally associated with an infant being in both the lowest quartile of fetal growth and the highest quartile of 0- to 6-month weight-for-length gain (Q4 vs. Q1, odds ratio = 3.01 [95% CI = 1.08 to 8.44]). Roadway proximity and 3rd-trimester black carbon exposure were similarly associated with growth outcomes. For 3rd-trimester particulate matter (PM2.5), effect estimates were in the same direction, but smaller and imprecise.
Infants exposed to higher traffic-related pollution in early life may exhibit more rapid postnatal weight gain in addition to reduced fetal growth.
Metrics
Details
- Title
- Prenatal exposure to traffic pollution: associations with reduced fetal growth and rapid infant weight gain
- Creators
- Abby F Fleisch - Boston Children's HospitalSheryl L Rifas-ShimanPetros KoutrakisJoel D SchwartzItai Kloog - Ben-Gurion University of the NegevSteven MellyBrent A CoullAntonella ZanobettiMatthew W Gillman - Harvard Pilgrim Health CareDiane R Gold - Brigham and Women's HospitalEmily Oken - Harvard Pilgrim Health Care
- Publication Details
- Epidemiology (Cambridge, Mass.), v 26(1), pp 43-50
- Publisher
- Lippincott
- Grant note
- P30DK092924 / NIDDK NIH HHS T32 HL007427 / NHLBI NIH HHS R01 HD034568 / NICHD NIH HHS K12DK094721-02 / NIDDK NIH HHS R37HD034568 / NICHD NIH HHS P01ES009825 / NIEHS NIH HHS P30 ES000002 / NIEHS NIH HHS R37 HL066289 / NHLBI NIH HHS R01 AI102960 / NIAID NIH HHS K12 DK094721 / NIDDK NIH HHS T32 HS000063 / AHRQ HHS R01AI102960 / NIAID NIH HHS T32HS000063 / AHRQ HHS K24 HD069408 / NICHD NIH HHS R37 HD034568 / NICHD NIH HHS P01 ES009825 / NIEHS NIH HHS P30 DK092924 / NIDDK NIH HHS K24HD069408 / NICHD NIH HHS P03ES000002 / NIEHS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000345878000019
- Scopus ID
- 2-s2.0-84979862419
- Other Identifier
- 991021875345404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health