Journal article
Prevalence, Incidence, and Persistence of Psychiatric and Substance Use Disorders Among Mothers Living With HIV
Journal of acquired immune deficiency syndromes : JAIDS, v 65(5), pp 526-534
15 Apr 2014
PMID: 24759063
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective: To evaluate prevalence, incidence, remission, and persistence of psychiatric and substance use disorders among HIV-infected mothers and identify biopsychosocial correlates.
Methods: HIV-infected mothers (n = 1223) of HIV-exposed uninfected children enrolled in a prospective cohort study; HIV-uninfected mothers (n = 128) served as a comparison group. Mothers provided sociodemographic and health information and completed the Client Diagnostic Questionnaire (CDQ). Prevalence of any psy-chiatric or substance use disorder at initial evaluation was compared between the 2 groups. Incident, remitting, and persisting disorders were identified for 689 mothers with HIV who completed follow-up CDQs. We used logistic regression to evaluate adjusted associations of biopsychosocial characteristics with presence, incidence, remission, and persistence of disorders.
Results: Thirty-five percent of mothers screened positive for any psychiatric or substance use disorder at initial evaluation, with no difference by maternal HIV status (P = 1.00). Among HIV-infected mothers, presence of any disorder was associated with younger age [adjusted odds ratio (aOR): 1.39; 95% CI: 1.09 to 1.75], single parenthood (aOR: 1.35; 95% CI: 1.08 to 1.68), and functional limitations (aOR: 2.29; 95% CI: 1.81 to 2.90). Incident disorders were associated with functional limitations (aOR: 1.92; 95% CI: 1.10 to 3.30). Among HIV-infected mothers with a disorder at initial evaluation (n = 238), 61% had persistent disorders. Persistent disorders were associated with lower income (aOR: 2.44; 95% CI: 1.33 to 4.76) and functional limitations (aOR: 3.19; 95% CI: 1.87 to 5.48). Receipt of treatment for any disorder was limited: 4.5% at study entry, 7% at follow-up, 5.5% at both entry and follow-up.
Conclusions: Psychiatric and substance use disorders remain significant comorbid conditions among HIV-infected mothers and require accessible evidence-informed treatment.
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Details
- Title
- Prevalence, Incidence, and Persistence of Psychiatric and Substance Use Disorders Among Mothers Living With HIV
- Creators
- Kathleen M. Malee - Institute of Behavioral SciencesClaude A. Mellins - Columbia University Irving Medical CenterYanling Huo - Cancer Research And BiostatisticsKatherine Tassiopoulos - Harvard UniversityRenee Smith - University of Illinois ChicagoPatricia A. Sirois - Tulane UniversitySusannah M. Allison - Office of AIDS ResearchDeborah Kacanek - Cancer Research And BiostatisticsSuad Kapetanovic - NIMH, NIH, Bethesda, MD 20892 USAPaige L. Williams - Harvard Univ, Sch Publ Hlth, Dept Biostat, Ctr Biostat AIDS Res, Boston, MA 02115 USAMitzie L. Grant - Drexel University, PsychiatryDaniel Marullo - Childrens Alabama, Dept Childrens Behav Hlth, Birmingham, AL USAAngela A. Aidala - Columbia Univ, Dept Sociomed Sci, Mailman Sch Publ Hlth, New York, NY USAPediat HIV AIDS Cohort Study PHACS
- Publication Details
- Journal of acquired immune deficiency syndromes : JAIDS, v 65(5), pp 526-534
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 9
- Grant note
- National Institute on Alcohol Abuse and Alcoholism; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Alcohol Abuse & Alcoholism (NIAAA) National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) National Heart Lung and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) Office of AIDS Research; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA HD052104; 3U01HD052104-06S1 / Tulane University School of Medicine National Institute on Drug Abuse; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA) Intramural Research Program of the National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) Eunice Kennedy Shriver National Institute of Child Health and Human Development; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) National Institute of Dental and Craniofacial Research; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Dental & Craniofacial Research (NIDCR)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry
- Web of Science ID
- WOS:000337684400007
- Scopus ID
- 2-s2.0-84898749277
- Other Identifier
- 991019167778404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Infectious Diseases