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Priapism in a 31-Year-Old Male With Paranoid Schizophrenia
Journal article   Open access   Peer reviewed

Priapism in a 31-Year-Old Male With Paranoid Schizophrenia

CUREUS JOURNAL OF MEDICAL SCIENCE, v 15(11), e48978
17 Nov 2023
PMID: 38111440
url
https://doi.org/10.7759/cureus.48978View
Published, Version of Record (VoR) Open

Abstract

Priapism is a painful and emergent side effect that has been linked to some antipsychotics and other psychiatric medications, most often trazodone. This is thought to be due to some level of alpha-1 adrenergic blockade by these medications. Aripiprazole is an atypical antipsychotic with notably weak alpha-1 adrenergic antagonism. Thus, we report on a unique case of aripiprazole-induced priapism in a patient with schizophrenia and recurrent episodes of antipsychotic-induced priapism. This study offers insight into the potential mechanism of aripiprazole-induced priapism and offers alternative medications, such as olanzapine and lumateperone, to treat the patient's ongoing psychotic disorder.

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#5 Gender Equality
#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Urology & Nephrology
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