Journal article
Printability in extrusion bioprinting
Biofabrication, v 13(3), pp 033001/1-033001/15
01 Jul 2021
PMID: 33601340
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Extrusion bioprinting has been widely used to extrude continuous filaments of bioink (or the mixture of biomaterial and living cells), layer-by-layer, to build three-dimensional constructs for biomedical applications. In extrusion bioprinting, printability is an important parameter used to measure the difference between the designed construct and the one actually printed. This difference could be caused by the extrudability of printed bioink and/or the structural formability and stability of printed constructs. Although studies have reported in characterizing printability based on the bioink properties and printing process, the concept of printability is often confusingly and, sometimes, conflictingly used in the literature. The objective of this perspective is to define the printability for extrusion bioprinting in terms of extrudability, filament fidelity, and structural integrity, as well as to review the effect of bioink properties, bioprinting process, and construct design on the printability. Challenges related to the printability of extrusion bioprinting are also discussed, along with recommendations for improvements.
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Details
- Title
- Printability in extrusion bioprinting
- Creators
- Zhouquan Fu - Drexel UniversitySaman Naghieh - University of SaskatchewanCancan Xu - SunP Biotech LLC, 5 Allison Dr, Cherry Hill, New Jersey, 08003, UNITED STATES.Chengjin Wang - Tsinghua UniversityWei Sun - Drexel UniversityXiongbiao Chen - Univ Saskatchewan, Div Biomed Engn, Saskatoon, SK S7N 5A9, Canada
- Publication Details
- Biofabrication, v 13(3), pp 033001/1-033001/15
- Publisher
- Iop Publishing Ltd
- Number of pages
- 15
- Grant note
- RGPIN-2019-06396 / Natural Sciences and Engineering Research Council of Canada (NSERC) G2017002 / 111 Project from the Ministry of Education, China; Ministry of Education, China - 111 Project 260676 / Drexel University
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000639519100001
- Scopus ID
- 2-s2.0-85105289371
- Other Identifier
- 991019167812904721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Engineering, Biomedical
- Materials Science, Biomaterials