Journal article
Progress in material design for biomedical applications
Proceedings of the National Academy of Sciences - PNAS, v 112(47), pp 14444-14451
24 Nov 2015
PMID: 26598696
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Biomaterials that interface with biological systems are used to deliver drugs safely and efficiently; to prevent, detect, and treat disease; to assist the body as it heals; and to engineer functional tissues outside of the body for organ replacement. The field has evolved beyond selecting materials that were originally designed for other applications with a primary focus on properties that enabled restoration of function and mitigation of acute pathology. Biomaterials are now designed rationally with controlled structure and dynamic functionality to integrate with biological complexity and perform tailored, high-level functions in the body. The transition has been from permissive to promoting biomaterials that are no longer bioinert but bioactive. This perspective surveys recent developments in the field of polymeric and soft biomaterials with a specific emphasis on advances in nano- to macroscale control, static to dynamic functionality, and biocomplex materials.
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Details
- Title
- Progress in material design for biomedical applications
- Creators
- Mark W Tibbitt - Massachusetts Institute of TechnologyChristopher B Rodell - University of PennsylvaniaJason A Burdick - University of PennsylvaniaKristi S Anseth - University of Colorado Boulder
- Publication Details
- Proceedings of the National Academy of Sciences - PNAS, v 112(47), pp 14444-14451
- Publisher
- PNAS
- Grant note
- R01 HL111090 / NHLBI NIH HHS R01 EB008722 / NIBIB NIH HHS F32 HL122009 / NHLBI NIH HHS R01 DE016523 / NIDCR NIH HHS R01 AR056624 / NIAMS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000365173100037
- Scopus ID
- 2-s2.0-84948410667
- Other Identifier
- 991019176797104721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Materials Science, Multidisciplinary