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Progressive peripheral agraphia
Journal article   Peer reviewed

Progressive peripheral agraphia

M Grossman, D J Libon, X S Ding, B Cloud, J Jaggi, D Morrison, J Greenberg, A Alavi and M Reivich
Neurocase, v 7(4), pp 339-349
01 Jan 2001
DOI: https://doi.org/10.1076/neur.7.4.339.16253
PMID: 11557829

Abstract

Clinical Neurology Life Sciences & Biomedicine Neurosciences & Neurology Psychiatry Psychology Science & Technology Social Sciences
We describe RW, a patient who presented with writing difficulty that deteriorated over time. While her graphemes were typically legible, her writing was extremely slow, and her letters were written in an inconsistent and heterogeneous manner (e.g. each 'a' in the word 'banana' was produced in a different way). Her mental imagery of letters was impoverished, and she also produced allographic errors in her writing. She had some spelling errors as well, but many of these were due to omissions, perseverations, and motor operations. A positron emission tomography scan demonstrated superior parietal occipital and superior frontal defects that were more evident on the left than the right. Our observations are consistent with the hypothesis that RW has a deficit retrieving physical letter forms as manifested by her heterogeneous and slow production of letter forms. This disruption of grapheme retrieval is associated with interruption of a superior frontal-parietal system in the left hemisphere.

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Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
Psychiatry
Psychology
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