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Prospective Diagnosis of Pseudohypoaldosteronism
Journal article   Peer reviewed

Prospective Diagnosis of Pseudohypoaldosteronism

ALAN M. Schindler and GARRETT E. Bergman
Pediatrics (Evanston), v 78(3), pp 516-518
01 Sep 1986
PMID: 3529026

Abstract

Pseudohypoaldosteronism is characterized by salt wasting in spite of elevated plasma renin activity and serum aldosterone concentration. If the salt wasting is severe, pseudohypoaldosteronism may present as early as the first or second week of life. We were able to demonstrate pseudohypoaldosteronism on the second day of life in an asymptomatic newborn baby whose father and 1-year-old sister were known to have pseudohypoaldosteronism. CASE REPORTS Case 1 The patient was a 6-week-old white girl, who was born at term. Her mother was 24 years old, primigravida, and had an uncomplicated pregnancy. The baby was admitted to the hospital for evaluation of lethargy, poor feeding, vomiting, and failure to thrive when fed breast milk and, later, a proprietary formula.

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