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Prospective study of voice outcomes and patient tolerance of in-office percutaneous injection laryngoplasty
Journal article   Peer reviewed

Prospective study of voice outcomes and patient tolerance of in-office percutaneous injection laryngoplasty

Hakan Birkent, Maya Sardesai, Amanda Hu and Albert L. Merati
The Laryngoscope, v 123(7), pp 1759-1762
01 Jul 2013
PMID: 23606269

Abstract

Life Sciences & Biomedicine Medicine, Research & Experimental Otorhinolaryngology Research & Experimental Medicine Science & Technology
Objectives/Hypothesis In-office percutaneous injection laryngoplasty is a common treatment for glottal insufficiency. Our objective was to prospectively study voice outcomes and patient tolerance of the procedure. Study Design Prospective case series. Methods Consecutive adult patients undergoing awake injection laryngoplasty were recruited. Voice Handicap Index (VHI)-30; Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V); and vocal Grade, Roughness, Breathiness, Asthenia and Strain (GRBAS) were evaluated prior to injection and 2 months postinjection. Visual analog scale (VAS) was completed by the patient before and after the procedure to quantify the amount of discomfort. Results Thirty-five subjects enrolled; 26 (15 male, 11 female; mean age 61.6 +/- 13.2 years) had complete data. All components of VHI improved significantly: functional (P=0.0006), emotional (P=0.0004), physical (P=0.009), and total (P=0.0006). CAPE-V also improved significantly (P=0.003). All components of GRBAS, except for roughness, improved significantly: grade (P=0.004), roughness (P=0.718), breathiness (P=0.023), asthenia (P=0.023), and strain (P=0.03). Patient expectations on the tolerance of the procedure was similar to what they reported immediately afterward (P=0.803). Conclusions Injection laryngoplasty is an effective method of treating glottal insufficiency, as measured by voice outcomes. Patients have realistic expectations on the procedure experience and find it tolerable. This is the first prospective study of injection laryngoplasty outcomes. Level of Evidence 4. Laryngoscope, 2013

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Medicine, Research & Experimental
Otorhinolaryngology
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