Journal article
Prostate Brachytherapy After Ileal Pouch–Anal Anastomosis Reconstruction
Urology (Ridgewood, N.J.), v 73(2), pp 369-373
01 Feb 2009
PMID: 18708241
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To determine the safety of prostate brachytherapy in patients with clinically localized prostate cancer who have undergone proctocolectomy with ileal pouch–anal anastomosis (IPAA).
We performed a retrospective chart review of patients with a prior history of IPAA reconstruction who underwent prostate brachytherapy at our institution. Clinical records were reviewed for demographic characteristics, postoperative dosimetry, changes in bowel function, and oncologic outcomes. Data were analyzed using descriptive statistics.
Five patients with an IPAA underwent prostate brachytherapy for clinically localized prostate cancer. Mean time from colorectal reconstruction to prostate brachytherapy was 6.3 years. Adequate dosimetry (mean D90 114.9%, mean V100 91.1%, mean R100 0.76 mL) was achieved in each patient. Bowel frequency worsened in the immediate postoperative period in all patients, but all patients returned to their baseline bowel pattern by 4 months after their procedure. Serious complications, such as J-pouch ulcers, fistulas, or fecal incontinence, did not occur in these patients.
Prostate brachytherapy is a safe treatment option in patients with clinically localized prostate cancer and a history of proctocolectomy and IPAA reconstruction.
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Details
- Title
- Prostate Brachytherapy After Ileal Pouch–Anal Anastomosis Reconstruction
- Creators
- Richard Williamson - University of PittsburghMarc C. Smaldone - University of PittsburghErin P. Gibbons - University of PittsburghRyan P. Smith - University of Pittsburgh Medical CenterSushil Beriwal - University of Pittsburgh Medical CenterRonald M. Benoit - University of Pittsburgh School of Medicine
- Publication Details
- Urology (Ridgewood, N.J.), v 73(2), pp 369-373
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000264038100042
- Scopus ID
- 2-s2.0-58649101599
- Other Identifier
- 991021897284304721
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- Web of Science research areas
- Urology & Nephrology