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Psychosocial Factors and Risk of Incident Heart Failure The Multi-Ethnic Study of Atherosclerosis
Journal article   Open access   Peer reviewed

Psychosocial Factors and Risk of Incident Heart Failure The Multi-Ethnic Study of Atherosclerosis

Rachel P. Ogilvie, Susan A. Everson-Rose, W. T. Longstreth, Carlos J. Rodriguez, Ana V. Diez-Roux and Pamela L. Lutsey
Circulation. Heart failure, v 9(1), pp e002243-e002243
01 Jan 2016
DOI: https://doi.org/10.1161/CIRCHEARTFAILURE.115.002243
PMID: 26699386
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1161/circheartfailure.115.002243View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze),  Open
url
https://doi.org/10.1161/CIRCHEARTFAILURE.115.002243View
Published, Version of Record (VoR) Open

Abstract

Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology Life Sciences & Biomedicine Science & Technology
Background-Heart failure (HF) is a major source of morbidity and mortality in the United States. Psychosocial factors have frequently been studied as risk factors for coronary heart disease but not for HF. Methods and Results-We examined the relationship between psychological status and incident HF among 6782 individuals from the Multi-Ethnic Study of Atherosclerosis (MESA). Anger, anxiety, chronic stress, depressive symptoms, and hostility were measured using validated scales, and physician reviewers adjudicated incident HF events. Cox proportional hazards models were used to adjust for relevant demographic, behavioral, and physiological covariates. Interactions by age, race, sex, and self-reported health were examined in exploratory analyses. During a mean follow-up of 9.3 years, 242 participants developed incident HF. There was no association between psychosocial factors and HF hazard ratios (95% confidence interval) for the highest versus lowest quartile: anger=1.14 (0.81-1.60), anxiety=0.74 (0.51-1.07), chronic stress=1.25 (0.90-1.72), depressive symptoms=1.19 (0.76-1.85), and hostility=0.95 (0.62-1.42). In exploratory analysis, among the participants reporting fair/poor health at baseline, those reporting high versus low levels of anxiety, chronic stress, and depressive symptoms had 2-fold higher risk of incident HF, but there was no association for those with good/very good/excellent self-reported health. Conclusions-Overall, these psychosocial factors were not significantly associated with incident HF. However, for participants reporting poor health at baseline, there was evidence that anxiety, chronic stress, and depressive symptoms were associated with increased risk of HF. Future research with greater statistical power is necessary to replicate these findings and seek explanations.

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15 Record Views
36 citations in Web of Science
38 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Cardiac & Cardiovascular Systems
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